Possible involvement of α1-adrenergic receptor and KATP channels in cardioprotective effect of remote aortic preconditioning in isolated rat heart

Authors

  • Rajeev Taliyan, Manjeet Singh, Pyare Lal Sharma, Harlokesh Narayan Yadav, Kulwinder Singh Sidhu Author

Keywords:

Cardio-protection, ischemic preconditioning, ischemia / reperfusion injury, remote aortic preconditioning

Abstract

Coronary artery disease represents a global burden on health care resources, and it is the leading cause of morbidity and mortality in the world by 2020.[1] Repeated short episodes of ischemia and reperfusion have been demonstrated to make myocardium transiently more resistant to deleterious effects of prolonged ischemia and this paradoxical form of myocardial adaptation has been termed as ischemic preconditioning.

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Published

2010-05-10

Issue

Vol. 1 No. 3 (2010): Volume 1 Issue 3 (2010)

Section

Articles