Doxorubicin-Loaded Aptamer S3-Linked DNA Tetrahedrons for Targeted Therapy of Nasopharyngeal Carcinom.
DOI:
https://doi.org/10.48047/Keywords:
Nasopharyngeal carcinoma, Aptamer S3, CD109, 5-8F cells, DNA tetrahedrons, Doxorubicin.Abstract
Objective: Our research group previously identified CD109 as the target of aptamer S3 in
nasopharyngeal carcinoma (NPC). This study aimed to develop a targeted delivery system by
conjugating aptamer S3 to DNA tetrahedrons (DTs) loaded with doxorubicin (Dox), and to
evaluate the potential of S3-DT-Dox for targeted NPC therapy.
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Published
2013-08-10
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