Correlation between Lipid Profile and HbA1c in Type 2 Diabetic Patients

Abstract

Background: Dyslipidemia is a very common finding in patients with type 2 Diabetes Mellitus (DM) which strongly increases risk for the development of cardiovascular diseases. Objectives: The aim of this study was to determine the pattern of dyslipidemia and to establish the correlation between glycated haemoglobin (HbA1c) and lipid profile in type 2 DM patients. Methods: In this cross sectional study 300 patients with type 2 DM were analyzed for HbA1c level, fasting blood sugar (FBS), total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) levels. A correlation between the variables was done by Pearson’s correlation analysis. Results: The significantly low mean values of FBS, total Cholesterol, TGs and LDL and high mean values of HDL were observed in patients with good glycemic control (HbA1c≤7) than those with poor glycemic control (HbA1c>7%). A significant positive correlation was found between HbA1c with FBS, TC, TG, LDL, VLDL and significant negative correlation with HDL level (p<0.05). Conclusion: There is positive correlation between level of glycemic control (HbA1c) and severity of dyslipidemia in patients of type 2 DM.