“ASSESSMENT AND EVALUATION OF SERUM LIPID PROFILE IN PREGNANCIES COMPLICATED BY PRE-ECLAMPSIA: A TERTIARY CARE HOSPITAL BASED STUDY”

Abstract

Pre-eclampsia is the most common complication of pregnancy that leads to considerable morbidity and mortality in both the mother and the foetus. Preeclampsia is a multisystem condition associated with pregnancy that goes away after delivery and is marked by hypertension and proteinuria. Our goal was to examine the changes in lipid profiles between pre-eclampsia and a typical pregnancy. According to the current study, the woman who developed pre-eclampsia may have had abnormal
lipid metabolism, which resulted in a distinct lipid profile. An association exists between pregnancy and physiological hyperlipidemia. Pregnancyinduced hypertension is caused by abnormal increases in triglycerides, LDL, VLDL, and total cholesterol, which in turn stimulate oxidative stress and vascular dysfunction. In order to reduce obstetric complications including eclampsia, antepartum haemorrhage, and preterm labour linked to preeclampsia, evaluation of the blood lipid profile in pregnant women during early antenatal visits may help in the prediction and early identification of pre-eclampsia.