Left ventricular structure and function in prediabetic adults:Relationship with insulin resistance

Abstract

Several studies have shown that ventricular dysfunction is increased in individuals with diabetes. Insulin resistance (IR) may precede type 2 diabetes, and is a pathogenic factor for it. Furthermore, IR has been shown to be an independent predictor of cardiovascular disease in diabetes. Given that glucose intolerance and IR precede the development of overt diabetes, these factors would be associated with abnormal myocardial performance