STUDY OF EFFICACY OF DEXMEDETOMIDINE AND CLONIDINE IN ATTENUATING THE HAEMODYNAMIC RESPONSE DURING LARYNGOSCOPY AND INTUBATION

Abstract

Endotracheal intubation started in last quarter of 19th century, it is one of the most performed procedure in the field of anaesthesia. It is nothing but placement of endotracheal tubes of appropriate size orally or via nasal route. It involves direct laryngoscopy for visualisation of vocal cord. These processes of laryngoscopy and translaryngeal placement of endotracheal tube are noxious stimulus to the tracheal and laryngeal mucosa. Following these stimulus there is increase sympathetic and sympathoadrenal activity as evidenced by increase in plasma catecholamine concentration