Anti-RA33 Antibody is More Sensitive than AntiCitrullinated Protein Antibody in Diagnosis of Rheumatoid Arthritis

Abstract

: To avoid Rheumatoid arthritis (RA)progression and disability, disease should be detected as early as possible, which needs diagnostic biomarkers which can dependably anticipate early RA and its progression, autoantibodies are one of the most reliable diagnostic markers that can be used. Anti-citrullinated protein/peptide antibodies (ACPA) are one of serological markers of RA. In addition anti-RA33 antibody (Ab) is another serological marker in RA but its diagnostic utility still dialectical, as it was present in a patients with small proportion.