Journal of Cardiovascular Disease Research
A COMPARATIVE STUDY OF HYPERBARIC BUPIVACAINE AND LEVOBUPIVACAINE IN LOWER LIMB SURGERIES UNDER SPINAL ANAESTHESIA
Aryaa Ram Godhane, Mayuri Pore, Aarif Rangrez, Razziuddin Shaikh, Hasnat Ansari
JCDR. 2024: 970 -978
Abstract
Background: Hyperbaric racemic bupivacaine is commonly used for spinal anaesthesia however racemic bupivacaine has some drawbacks. It has a high propensity to cause hypotension and bradycardia following intrathecal injection, and catastrophic cardiac toxicity due to the high affinity to cardiac myocytes. Levobupivacaine has a lower affinity for cardiac sodium channels. thus, reducing the risk of cardio toxicity. Aim: To compare Intraoperative quality, duration & complications of anaesthesia in patients undergoing lower limb surgeries with hyperbaric racemic bupivacaine and levobupivacaine administered intrathecally.
» PDF