Journal of Cardiovascular Disease Research
Age-Related Histological and Functional Alterations in Liver Tissues: A Cross-sectional Study of Fibrosis, Lipid Accumulation, and Oxidative Stress Markers
Mukesh Pratap Sah, Dr Mahakal Singh Chandel, Prof. Dr. Avantika Bamniya
JCDR. 2024: 823-831
Abstract
Background: Liver aging entails structural and functional changes that may increase susceptibility to diseases such as non-alcoholic fatty liver disease (NAFLD) and cirrhosis. These changes, including fibrosis, lipid accumulation, hepatocyte hypertrophy, and oxidative stress, complicate clinical differentiation between normal aging and pathological liver conditions in older adults.
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