Abstract

Aim: To determine the standardized reference range for HOMA – IR among apparently normal population of Ottappalam. Methodology: 100 apparently normal subjects were selected and subjected to blood pressure measurement, Weight and height, BMI, Triglyceride, HDL and LDL cholesterol and HOMA – IR was calculated. Results: Age group 20-25 years had 5%, 26-30 years had 80%, 31-35 years had 9%, 36-40 years had 3% and >40 years had 3% patients. The mean age was 28.78 years. Most of the subjects taken for the study were females – 62%. Most of the subjects were in the 18.5 – 22.9 kg/m2 group (94%). Minimum value of HOMA – IR was 0.74 and maximum value was 5.38. Mean HOMA – IR for the apparently normal population of Ottappalam was calculated as 2.65. Range for HOMA – IR according to 95% confidence intervals was 2.46 to 2.84. HOMA – IR had a positive correlation with age, which means as age advances the insulin resistance also rises, p value for this observation being 0.023. HOMA – IR had a positive correlation with BMI, p value being <0.001. HOMA – IR had a positive correlation with both systolic and diastolic BP. Fasting plasma insulin levels had positive correlation with BMI, systolic and diastolic blood pressures.

Description

.