Journal of Cardiovascular Disease Research
Comparison of the Efficacy of Intravenous (IV) Infusion of Dexmedetomidine and Intravenous (IV) Infusion of Nitroglycerine for Controlled Hypotensive Anaesthesia in Elective Spine Surgeries
Dr. Danish Omair, Dr. R S Sachidanand, Dr. Sumedha Vangala
JCDR. 2024: 164 -172
Abstract
BACKGROUND Induced hypotension limits intra-operative blood loss to provide better visibility of the surgical field and diminishes the incidence of major complications during spine surgeries. Nitroglycerine (NTG) is a well-established vasodilator that acts by reducing increasing the venous capacitance and reducing preload and cardiac output, thereby reducing the arterial blood pressure and dexmedetomidine, a selective α2 agonist has sympatholytic action and thus induce hypotension, so these 2 drugs have been used in this study to induce hypotensive anaesthesia.
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