Abstract

Background: To study Nucleated Red Blood Cells as predictor of prognosis & mortality risk in critically ill patients. Material and Methods: Critically ill patients with A.P.A.C.H.E II score > 25 were enrolled in the study. NRBC positive & NRBC negative groups were made. Prognosis & Mortality of both groups were compared and analyzed. Results: N.R.B.C was absent in 144 (72%) patients whereas present among 56 (28%) patients including 41 (28.87%) male patients whereas 15 (25.86%) female patients. The patients in whom N.R.B.C was present reported mean age as 58.97 years whereas not having N.R.B.C was 57.29 years. The patients with N.R.B.C reported mean BMI as 26.33Kg/m2 whereas, the patients without N.R.B.C was 25.95Kg/m2. N.R.B.C was present among patients having pulmonary diseases (28.57%) followed by gastrointestinal diseases (21.43%) and acute coronary syndrome (16.07%). Patients with N.R.B.C was present reported mean intensive care treatment (days) as 8.22 days whereas patients without N.R.B.C was 3.41 days with p<0.01. The patients with N.R.B.C reported mean A.P.A.C.H.E. II score to be 31.67 whereas not having N.R.B.C was 25.49. N.R.B.C was present in 27(48.21%) patients who deceased whereas among 29 (51.79%) patients who being discharged. Area under the R.O.C curve was 0.894. N.R.B.C.s in blood showed sensitivity and specificity of 72.3% and 90.6%, respectively.

Description

.