Journal of Cardiovascular Disease Research
Pattern of Isoniazid Monoresistance among Pulmonary Tuberculosis Patients at Tertiary Care Centre
Dr Vibhuti Zankat, Dr Rashmika Parmar, Dr Hitesh Shingala, Dr Payal Mankodi
JCDR. 2024: 128 -139
Abstract
Introduction: Tuberculosis is an infectious disease, which remains killer disease of all times. Drug resistance in the first line drugs makes the situation worse. Major obstacle in the management of tuberculosis is emergence of drug resistance. The molecular line-probe assay provides rapid diagnosis and early management of MDR-TB. It detects mutations of katG and inhA genes associated with isoniazid (INH) resistance in Mycobacterium tuberculosis isolates.
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