Journal of Cardiovascular Disease Research
Significance of serum ferritin, interleukin 6 and erythrocyte sedimentation rate as a marker of COVID 19 disease Severity.
Mohd Kashif, Mohd Ashraf, Ashaq Hussain Parrey, Mohd Ismail, Basharat Kasana, Mir Sadaqat, Manzoor Koka, Syed Mahapara, Isma Shafi
JCDR. 2023: 1035-1041
Abstract
Inflammatory responses play a critical role in the COVID-19 disease. These Markers have been reported to be significantly associated with the high risks of developing severe COVID- 19. Our study highlights the role of interleukin 6 (IL6), erythrocyte sedimentation rate (ESR) and serum ferritin in predicting the severity COVID-19. Objectives To investigate and correlate inflammatory markers Erythrocyte sedimentation rate (ESR), Interleukin 6 and Serum Ferritin with the severity of Covid-19. Key words Covid 19, Interlukin6, Serum ferritin,Erythocyte sedmentation rate,Disease severity. Results Out of 307 patients, we found all the three inflammatory markers (IL6, ESR and serum ferritin) correlate with disease severity the mean ESR in mild, moderate and severe COVID 19 disease was 35,42 and 55.5 respectively. The mean IL6 in mild, moderate and severe COVID 19 disease was 14,33 and 61 respectively and the mean serum ferritin in mild, moderate and severe COVID 19 disease was 253,373 and 801 respectively. Conclusions These inflammatory parameters could be used in for prompt identification of severe covid-19 disease patients and subsequently triaging them for initiation of treatment protocols
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