Journal of Cardiovascular Disease Research
STUDY OF CRP AND LIPID PROFILE IN PATIENTS OF SUBCLINICAL HYPOTHYROIDISM
Dr Roshni Khundrakpam, Dr Kedar Balwant Joshi, Dr Bina Manoj Gadhiya
JCDR. 2024: 1188 -1196
Abstract
Background: Subclinical Hypothyroidism (SCH) is a prevalent condition globally, more common than overt Hypothyroidism. It is characterized by elevated thyroid-stimulating hormone (TSH) levels with normal peripheral thyroid hormone levels. Recent findings indicate that inflammation and disturbances in lipid metabolism play a role in the development of SCH. Low grade inflammation is indicated by increase in levels of a marker C reactive protein (CRP) produced by hepatocytes. CRP has been linked to cardiovascular disease (CVD). Dyslipidemia, which refers to abnormal lipid levels, has been commonly linked to Overt Hypothyroidism. However, its significance in subclinical hypothyroidism (SCH) is still a topic of debate.
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