Abstract

Microalbuminuria in hypertension has been described as an early sign of kidney damage and a predictor for end stage renal disease and cardiovascular disease. Thus, it is of great importance to study the association between urinary albumin creatinine ratio and progression of kidney disease in hypertensive patients. The presence of microalbuminuria has been shown to correlate with the other cardiovascular risk factors commonly seen in hypertensive patients. This fact indicates that the detection of an increased urinary albumin excretion could probably be the best index of an increased global cardiovascular risk in a hypertensive patient. BP control is accompanied by a fall in the content of albumin in urine. Agents with the capacity to block the renin-angiotensin system have shown a capacity to decrease urinary albumin excretion, which is independent of their ability to lower blood pressure. In the present study two groups of patients, 50 non diabetic hypertensive (case) and 50 non diabetic normotensive (control) were evaluated for urinary ACR in spot urinary sample and their eGFRwas calculated. Written informed consent was taken from all the candidates enrolled for the study. The approval of institutional thesis committee was obtained before the study.

Description