E-ISSN 0976-2833 | ISSN 0975-3583
 

Research Article 


A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME

PamulaReddy Bhavanam, B Prashanthi.

Abstract
SJS is a acute life-threatening disasters consequence of hypersensitivity reaction precipitated by certain drugs like NSAID compounds, antiepileptic and antibiotics. Age, nutrition status presence of co-morbidities are important co-factor for prognosis. Immune dysfunction mediated by T-Lymphocytes and oxidative stress generated are major cause. Ibuprofen is a common over the counter antipyretic analgesic NSAID. Hypersensitivity syndrome associated with Ibuprofen is a host dependent idiosyncratic drug reaction. A 30 year old female came to emergency department of a teaching hospital in Mahaboobnagar with chief complaints of appearance of blisters on oral mucosa after taking Ibuprofen 400mg tablets since 15days for joint pains . She developed multiple macular initially over face, lower limbs. Upon examination she had extensive erythema, necrosis. The body temperature was 100.40F, respiratory rate 24/min, Pulse rate 110 bpm. Upon laboratory examination her WBC levels also decreased along with rash, itching and serum uric acid was increased.

Key words: SJS, hypersensitivity, NSAID and WBC


 
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Pubmed Style

PamulaReddy Bhavanam, B Prashanthi. A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. J Cardiovasc. Dis. Res.. 2021; 12(6): 433-435. doi: 10.31838/jcdr.2021.12.06.56


Web Style

PamulaReddy Bhavanam, B Prashanthi. A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. http://www.jcdronline.org/?mno=9331 [Access: December 04, 2021]. doi: 10.31838/jcdr.2021.12.06.56


AMA (American Medical Association) Style

PamulaReddy Bhavanam, B Prashanthi. A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. J Cardiovasc. Dis. Res.. 2021; 12(6): 433-435. doi: 10.31838/jcdr.2021.12.06.56



Vancouver/ICMJE Style

PamulaReddy Bhavanam, B Prashanthi. A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. J Cardiovasc. Dis. Res.. (2021), [cited December 04, 2021]; 12(6): 433-435. doi: 10.31838/jcdr.2021.12.06.56



Harvard Style

PamulaReddy Bhavanam, B Prashanthi (2021) A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. J Cardiovasc. Dis. Res., 12 (6), 433-435. doi: 10.31838/jcdr.2021.12.06.56



Turabian Style

PamulaReddy Bhavanam, B Prashanthi. 2021. A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. Journal of Cardiovascular Disease Research, 12 (6), 433-435. doi: 10.31838/jcdr.2021.12.06.56



Chicago Style

PamulaReddy Bhavanam, B Prashanthi. "A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME." Journal of Cardiovascular Disease Research 12 (2021), 433-435. doi: 10.31838/jcdr.2021.12.06.56



MLA (The Modern Language Association) Style

PamulaReddy Bhavanam, B Prashanthi. "A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME." Journal of Cardiovascular Disease Research 12.6 (2021), 433-435. Print. doi: 10.31838/jcdr.2021.12.06.56



APA (American Psychological Association) Style

PamulaReddy Bhavanam, B Prashanthi (2021) A CASE REPORT ON IBUPROFEN INDUCED STEVEN JOHNSON SYNDROME. Journal of Cardiovascular Disease Research, 12 (6), 433-435. doi: 10.31838/jcdr.2021.12.06.56





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