Abstract

AIM : To compare Efficacy of Clindamycin 1% gel v/s Dapsone 5% gel in the Treatment of Mild to moderate acne vulgaris . METHODOLOGY: An prospective observational study was conducted in Dermatology department of IMCHRC Indore for a period of 18 months . All the adult patients with complaints suggestive of Patients of Mild to Moderate acne vulgaris . A total of 100 patients were involved in the study. RESULTS we can infer that when used as monotherapy, topical dapsone gel was found to be more effective in reducing the grade of acne when compared to topical clindamycin gel. The probable reason for this is the additional anti-inflammatory action of dapsone compared to the only anti bacterial action of clindamycin. Although dapsone gel was marketed as a novel drug, we in our study did not find any statistically significant results in favour of dapsonegel.

Description