Abstract

The prevalence of cervical cancer patients in India has varied from 87.8% to 96.67%. It has been studied that HPV-16 and 18 are the highly oncogenic types found in invasive cervical cancer and out of these two HPV-16 has been found more commonly. Materials and methods: This study is a hospital based cross-sectional study carried out in the Department of Pathology of Integral Institute of Medical Sciences and Research, Hospital, Lucknow. The institutional ethical committee approved the study. From March 2021 to September 2022, pap smears were collected from 47 patients attended OPD as well as IPD in Gynaecological department. Results: In the present for study the sensitivity, specificity, PPV and NPV for P16 was 95.0%, 42.89%, 35.29% and 92.31% respectively. Conclusion: The present study is undertaken to evaluate the diagnostic performance and Utility of p16 immunocytochemistry for triaging patients with epithelial cell abnormality of the cervix as the per 2014 Bethesda reporting system and identify premalignant and malignant lesions of the cervix and then follow up those cases and correlate with histopathological findings.

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