Abstract

Elevated levels of plasma D-dimer increase the risk of ischemic stroke, stroke severity, and the prognosis of stroke patient. The plasma D-dimer level increases during blood thrombosis and degradation of fibrin, hence it is a biological marker of haemostatic abnormalities and thrombosis. Association between plasma D-dimer level and functional outcome of acute ischemic stroke is unclear hence we have undertaken study to investigate whether plasma D-dimer level is a determinant of short-term poor functional outcome in patients with acute ischemic stroke (AIS). Methods: Present study was cross sectional in nature conducted on 100 AIS patients. All patients fulfilling inclusion criteria and exclusion criteria were taken up for the study. Results: In the present study, there was strong positive correlation of Modified Rankin Scale scores in patients with AIS with D dimer level (r=0.6; p=0.04) which means patients with poor short-term outcomes had significantly raised D dimer levels. Conclusion: Plasma D dimer level is determinant of short-term poor outcome & prognosis in patient with acute ischemic stroke.

Description