Abstract

Hypertensive disorders of pregnancy (HDP) are among obstetrics' most intriguing and yet unsolved problem. HDP is blood pressure greater than or equal to 140/90 mmHg, with each measurement usually corroborating within 4 hours. Hyperuricemia indicates kidney dysfunction in preeclampsia because of decreased glomerular filtration, decreased tubular secretion, and/or increased proximal tubular reabsorption. It is also an independent risk factor for cardiovascular diseases as it has been suggested that it alters vascular function and mediates vascular inflammation. As such, hyperuricemia can perhaps predict the severity of pre-eclampsia. Pre-eclampsia is also the most common cause of liver dysfunction in 3% of pregnancies because of micro vesicular fat deposition and reduced blood flow to the liver potentially causing ischemia and peri-portal haemorrhage

Description