Abstract

Oral cancer is one of the leading cancer today. The premalignant lesion is a disease or syndrome if left untreated have significantly increased risk to develop cancer. Aim and Objective of the study: The objective of this study is to find out the prevalence of oral cancer and to evaluate clinicopathological spectrum of oral cavity lesions at our tertiary care hospital. Materials and Methods: A detailed history-taking including age, sex, complaints and duration of symptoms, site, side etc. and with thorough clinical examination relevant investigations for consistency, diagnosis, benign or malignant was done and appropriate management has been done for these patients. All relevant investigations were done. Biopsy was done under local anaesthesia in the Dept. of Surgery and the specimen sent to Dept. of Pathology for histopathological examination. Results: In our cross-sectional study, we included a total of 100 subjects based on inclusion and exclusion criteria presenting to our OPD with oral cavity lesions, out of which 68% were males and 32% were females and majority of the subjects (37%) belong to the age group of 41-60 years. We evaluated all the subjects for oral cavity lesions with diagnostic biopsy and subjected for HPE. Among these subjects 36% had non-neoplastic lesion, 19% had benign lesion, 17% had pre-malignant and 28 % had malignant lesions. The most common pre-malignant lesion was leucoplakia, followed by oral lichen planus, oral sub mucous fibrosis, actinic cheilitis respectively and none had eryhthoplakia. Discussion and Conclusion: In our cross-sectional study, we included a total of 100 subjects based on inclusion and exclusion criteria presenting to our OPD with oral cavity lesions, out of which 68% were males and 32% were females. Among these subjects 36% had non-neoplastic lesion, 19% had benign lesion, 17% had pre-malignant and 28 % had malignant lesions. The most common pre-malignant lesion was leucoplakia, followed by oral lichen planus, oral sub mucous fibrosis, actinic cheilitis respectively and none had eryhthoplakia.

Description