Abstract

Inhalational anaesthetic agents like Desflurane and Sevoflurane are beneficial for early recovery after surgery, particularly in ambulatory procedures. The primary aim of this study was to compare the early recovery profiles of desflurane and sevoflurane in patients undergoing laparoscopic surgeries using a BIS monitor to assess the depth of anesthesia. Material and Methods: ASA I, II patients of 18-65 yrs. age undergoing laparoscopic surgeries were randomly allocated to received esflurane (n = 30) or sevoflurane (n = 30), using Bispectral Index System (BIS) to determine the depth of anesthesia. The study was conducted in Alluri Sitarama Raju Academy of Medical Sciences (ASRAM) over a period of one year, from February 2022 to January 2023. An in dependent adjudicator, who was blinded to the agent used, recorded the events during the recovery phase. The time required for spontaneous eye opening, response to painful stimuli, extubation, recall of name, and achievement of a modified Aldrete score of 9 were recorded. Results: The time required for an eye-opening and extubation was significantly shorter in the Desflurane group as compared to the Sevoflurane group [3.2 min ±0.71 versus6.13 min ±0.81, P = 0.001 and 5.7 min ± 0.81 versus9.3 min±1.2, P = 0.001]. A significantly higher mean modified Aldrete score was seen at extubation [9.6 min±0.81 vs 15.5 min ±1.54, P < 0.001] in the Desflurane group, which also achieved a modified Aldrete score of ≥9 significantly sooner [9.6 min ±0.81 vs 15.5 min ±1.54, P < 0.001] than the Sevoflurane group. The frequency of adverse effects was not significantly different in either of the groups. Conclusion: The usage of a BIS monitor reduces the incidence of intraoperative awareness, and also reduces the inhalational agent consumption by proper titration while maintaining BIS values of 40-60. Desflurane anesthesia enhances rapid emergence and recovery than sevoflurane anesthesia and facilitates early ambulation and discharge in laparoscopic surgeries

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