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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    A case control study to assess heart carotid pulse wave velocity and pulse transit time in triple vessel disease when compared to individuals without coronary artery disease


    DR.RAVINANDANA GOWDA H V, Dr. Sriranga Rangashamaiah Dr. NAGAMANI.A.C
    JCDR. 2023: 1385-1398

    Abstract

    Introduction: Coronary heart disease (CAD) is the leading cause of morbidity and mortality worldwide, with India being the top cause. The Asian subcontinent accounts for 20% of the world's population, but 60% of the cardiovascular disease burden is due to genetic predisposition and environmental factors. Arterial stiffness increases with aging, accelerated by cardiovascular risk factors like hypertension and diabetes. Endothelial dysfunction in coronary arteries affects arterial stiffness and potentially reversible in atherogenesis. Pressure wave velocity (PWV) is a useful index for assessing endothelial status and large artery stiffness. Large artery stiffening can increase systolic blood pressure, left ventricular afterload, and left ventricular hypertrophy, potentially limiting coronary perfusion.

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    Volume 14 Issue 7

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