Abstract

Fungal keratitis is a major ophthalmic problem worldwide specially in tropical and subtropical region. It is common in India due to the tropical climate and a large agrarian population that is at risk. Materials & Methods: The 3 cases for this case series we have taken from ophthalmology OPD having suspected fungal ulcer or vegetative trauma to the eye. Conjunctival swab cultures were carried out from affected eye and do the mycological investigations (10% KOH & culture over the SDA culture media) and clinically normal cases to study the fungal flora of conjunctival sac. Results: The fungal etiology in the causation of corneal ulcer varies in relation to age, sex and occupation of the patients and climatic condition of the region. The prevalence of mycotic corneal ulcer is more among male agriculture workers in the age group of 40 -60 years. Fungal corneal ulcer occurs more frequently during the harvesting season of the year. Minor vegetative trauma to cornea acts as precipitating factor of kerato mycosis mostly by the vegetative origin like paddy leaves straw, etc. Out of topical antifungal agents Fluconazole, Natamycin and voriconazole, Fluconazole has edge over Natamycin and Voriconazole in treating mycotic corneal ulcer.

Description