Abstract

When a previously normotensive and nonproteinuric woman suddenly develops hypertension with a blood pressure of 140/90 mm Hg or greater and proteinuria after the 20th week, this is called a multisystem illness of unclear cause. Hypertension brought on by the gravida state is called pregnancy-induced hypertension (PIH). Pre-eclampsia, eclampsia, and gestational hypertension are all part of this condition. Methods: The current study was undertaken to study the fetal and maternal outcome in pre-eclampsia with elevated d-dimers among patients of Government General Hospital, Kakinada. Hospital based prospective observational study. Patients admitted to inpatient ward in the dept. of Obstetrics and Gynecology, GGH, Kakinada from October 2020 to October 2022 with clinical diagnosis of pre-eclampsia in 100 patients. Results: Majority of the study subjects 42% belong to age group og 21-25 years, 30% belong to low SES, 57% were primigravida, 21% belong to 36 weeks, 52% presenting complaint is headache, Mean platelet value is 140479 ± 78931.32 SD, D-dimer values of 1701-2000 ng/ml. Mean D-dimer value is 2076 ± 632 SD. 49% normal vaginal delivery, new-born 72% were pre-term, new-born 73% were low-birth weight. Maternal complications is seen in 33% of study subjects. Fetal and Maternal Mortality rate is 5% each in the study. Conclusion: Maternal and fetal mortality rate is 5% each in the present study. Elevated-D dimers were significantly associated with maternal mortality. Elevated-D dimers were significantly associated with abnormal fetal outcome.

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