Abstract

This study was conducted with the aim to evaluate the frequency and patterns of different cutaneous granulomatous lesions with its clinico-histopathological correlation to reach etiological diagnosis. Materials and Methods: The present cross-sectional observational was conducted in the Department of Pathology, Mamata Academy of Medical Sciences, Hyderabad for the period of 1 year. This study enrolled 100 cases of skin biopsies after histopathological confirmation of granulomatous lesions. Results: 100 cases were studied in which male predominance was noted in 64 (64%) cases and females constituted 36 (36%) cases. Most of the patients were noted in age group of 21 to 31 years i.e 36 (36%) cases followed by 20 (20%) cases in 31 to 41years. 86% of cases were seen below 50 years of age in our study. Leprosy remained the significant causative reason for infectious granulomatous dermatoses succeeded by tuberculosis of skin. Borderline tuberculoid leprosy was found to be predominant, constituting 24 (24%) cases followed by indeterminate type 22 (22%) cases and lepromatous leprosy 21 (21%) cases, tuberculoid leprosy 18 (18%) cases and 8 (8%) cases of borderline lepromatous leprosy. Lupus vulgaris constituted 2 cases (2%) and only 2 (2%) case of sarcoidosis was found. Conclusion: Leprosy was the most common cause of cutaneous granuloma followed by Tuberculosis, fungal infection and foreign body reaction. Among the cases of leprosy, borderline tuberculoid leprosy and tuberculoid leprosy were the commonest subtype.

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