Abstract

To find out efficacy of MPI in comparison to APACHE II to prognosticate perforation peritonitis. Material and Method: The present cross sectional observational study was conducted among 100 patients admitted in Dept. of Surgery with hollow viscus perforation from 1 October 2019 till 30st September 2022. APACHE II and Mannheim Peritonitis Index (MPI) scoring systems was calculated in all the patients in order to assess their individual risk of morbidity and mortality. All the patients were subjected to emergency surgery. Outcome variables assessed were post-operative wound infection, wound dehiscence, anastomotic leak, respiratory complications, duration of hospital stay, need of ventilator support and mortality. Results: A total of 76 (76%) patients survived while 24 (24%) died during the hospital stay. Among 43 patients with MPI >30, a total of 19 (44.19%) died. Statistically, the association between APACHE II scores and mortality was significant (p<0.001). The sensitivity, specificity, positive predictive value and negative predictive value of MPI in the present study is 100%, 89%, 72%, 100% respectively. The accuracy rate of MPI is 70%. The sensitivity, specificity, positive predictive value and negative predictive value of APACHE II in the present study is 87%, 100%, 100%, 94% respectively. The accuracy rate of APACHE II is 84.50%. Conclusion: The findings of the study showed that both MPI as well as APACHE II were good predictors of outcome among patients with perforation peritonitis, however, APACHE II had a slightly higher sensitivity as well as specificity as compared to MPI

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