Abstract

Objectives: We conducted this study to compare the efficacy of Tapentadol Nasal Spray and Intramuscular injection diclofenac sodium as an analgesic for post-operative patients undergoing various elective and emergency surgeries. Methods: Using randomized controlled trial, sequentially numbered, opaque sealed envelopes (SNOSE) technique, half set of post-operative cases were prescribed tapentadol nasal spray and were assigned as Group A.Rest half of postoperative cases were prescribed intramuscular diclofenac sodium and were assigned as Group B. Scheduled dose of tapentadol nasal spray was 22.5 mg in each nostril and for intramuscular diclofenac dose was 75 mg. Results: The mean pain score was found less in the tapentadol nasal spray group compared to the intramuscular diclofenac sodium group at all intervals by VAS.(p<0.05). Conclusion: The results of the study show that patients who were given tapentadol nasal spray post operatively were found to have ease in administration of medication,early onset of analgesia and significantly better VAS and VPIS scores . Tapentadol Nasal Spray provides effective and better analgesia in the post operative pain management than intramuscular diclofenac with no major adverse effects.It also has early onset of analgesia and has ease in administration to patient.

Description

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