Abstract

The aim of present study is to compare study of dexmedetomidine and labetalol for attenuation of haemodynamic stress response to laryngoscopy and intubation. 90 ASA I and II patients aged15– 60 years undergoing elective ENT surgeries (mastoidectomy, FESS, stapedectomy and myringoplasty) under general anesthesia were chosen for the study. After obtaining ethics committee approval, the study population was chosen. All the patients were assessed preoperatively with history, clinical examination, and required investigations Result: The mean heart rate, mean systolic and mean diastolic blood pressure after injection. There is statistically significant difference in mean heart rate of patients across 3 groups (p< 0.01). The mean heart rate of group D is lower than that of both the group L and P. There is no statistical difference in the mean systolic diastolic blood pressure and SPO2 among 3 groups. Conclusion: 90 ASA I and II patient’s aged15– 60 years undergoing elective ENT surgeries (mastoidectomy, FESS, stapedectomy and myringoplasty) under general anesthesia were chosen for the study. After obtaining ethics committee approval, the study population was chosen. Informed written consent obtained from the patient. Heartrate, systolic and diastolic blood pressure and oxygen saturation were recorded as base line value. Dexmeditomidine 1µ/Kg given slowly over 10 minutes intravenously 5 minutes prior to induction, attenuates the cardiovascular responses to laryngoscopy and intubation in a better manner than Labetalol 0.5mg/Kg.

Description