Abstract

Regional anaesthesia is the preferred technique for most of the lower abdomen and lower limb surgeries. This study is to evaluate the efficacy, duration of analgesia and safety profile of bupivacaine heavy, bupivacaine heavy with Clonidine in 2 different doses in lower limb surgeries done under spinal anaesthesia. Material and Methods: 177 patients (ASA grade І & II), aged of 20-65 years of either sex scheduled for lower limb surgeries were randomly divided by envelop method into 3 groups of 59 patients each. Group I was given 15 mg 0.5% bupivacaine heavy with 0.5 ml normal saline.GroupII received 15 mg 0.5% bupivacaine heavy with 15 mcg Clonidine and group III was given 15 mg 0.5% bupivacaine heavy with 30 µg Clonidine for subarachnoid block. Time of onset of sensory block upto t10, time of onset of motor block, duration of motor block, duration of analgesia were noted. Results: supplementation of hyperbaric bupivacaine with clonidine in doses of 15 mcg and 30 mcg given intrathecally in spinal anaesthesia produces statistically significant shorter onset of sensory and motor block with longer duration of sensory and motor block when compared to bupivacaine alone (p<0.005). Conclusion: Clonidine15 mcg as adjuvant to hyperbaric bupivacaine provides maximum benefit with minimal side effect as compared to clonidine 30 mcg dose.

Description