ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    A Comparative Study to Evaluate Efficacy of IV Infusion of Dexmedetomidine versus IV Infusion of Propofol for Post-Operative ICU Sedation: An Original Research


    Dr. Bheemanadhuni Anusha, Dr. Potlapelly Vasu Prakash, Dr. Voviliveni Srikala, Dr Chandrashekhar Botla, Dr Sreenivas Azmeera
    JCDR. 2024: 420-425

    Abstract

    Objective: This study aimed to compare the efficacy and safety of intravenous (IV) infusion of dexmedetomidine versus IV infusion of propofol for post-operative sedation in the intensive care unit (ICU). Methods: A prospective, randomized controlled trial was conducted involving 300 postoperative ICU patients. Patients were randomly assigned to receive either dexmedetomidine or propofol for sedation. Sedation depth was assessed using the Richmond Agitation-Sedation Scale (RASS), monitoring vital signs, and adverse events. Baseline demographic data, including age, sex, BMI, comorbidities, surgery duration, and APACHE II scores, were recorded. Statistical analysis employed t-tests, chi-square tests, and Fisher's exact tests for comparison.

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    Volume 15 Issue 3

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