Abstract

Cerebrovascular accident or stroke is defined as abrupt onset of focal neurological deficit that is attributable to vascular cause, accounting for second leading cause of global mortality. Inflammation is the key for atherosclerosis pathogenesis with neutrophil lymphocyte ratio being the indicator of systemic inflammatory response and serving as prognostic biomarker in ischemic events. Methodology: A descriptive study was done among the cerebrovascular accident patients, excluding those with acute and chronic diseases of infective, inflammatory, hepatic and renal disease. History and clinical examination along with radio imaging was used for the diagnosis of CVA*. Neutrophil Lymphocyte Ratio was calculated on admission. The functional outcome of the patients was assessed using Modified Rankin Scale which was administered both during admission as well as at 7 days/discharge. Results: 45 to 75 years was the age range of the study participants and majority 66% were males, remaining females, 96% presented with ischemic stroke only 4% had haemorrhagic stroke. Mean Modified Rankin Scale score of 3.3 ± 0.8 and 2.8±1.3 was found at admission and day 7/discharge respectively. A highly significant positive correlation between the Neutrophil Lymphocyte ratio at admission and Modified Rankin Scale score at day 7/discharge was found. Majority of participants remained in static functional outcome group followed by improved group, as we measured outcome on day 7 or discharge whichever is earlier. Conclusion: As Neutrophil Lymphocyte ratio is cost effective and easily obtainable inflammatory marker that can be used to predict short term prognosis in acute cerebrovascular accident patients

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