Abstract

Background: Post operative sore throat (POST) is a common issue encountered in patients undergoing surgery under general anaesthesia with endotracheal tube. Our study aimed to evaluate efficiency of Zn lozenges on post operative sore throat by comparing it with placebo. Method: Total 80, ASA I and ASA II, patients of age group 20 to 60 years, posted for surgery lasting for 1 to 4 hours under general anaesthesia with endotracheal intubation were randomly allocated in two groups, group Zn (patients receive Zn lozenges in preoperative period) and group P (received placebo preoperatively). Incidence rate and severity score of POST at 0, 2, 4 and 24 hr postoperatively were observed. SPSS17.0 version used. Student’s T test and Mann Whitney U test used for continuous variables. Nominal categorical data compared using Chi-square and Fisher’s exact test. P<0.05 considered statistically significant. Result: The overall incidence of POST in group Zn and group P was 15% and 37.5%, respectively (p <0.05). We found statistically significant difference in incidence of mild POST between groups at 0, 2, 4 hours postoperative. The incidence of moderate POST, at different interval of time, was found to be more in group P but the difference was statistically insignificant. No incidence of severe POST reported in both the groups. Conclusion: Zn lozenges helps to alleviate POST.

Description