Abstract

An important development in the recent years is the observation that relative small elevation of serum creatinine has been associated with worsening of outcome in various diseases. Acute kidney injury is recognized as a contributor to unfavorable outcome in different clinical settings and should be considered as a risk factor for mortality in a host of clinical entities. AKI is observed in 7% of patients requiring hospitalization and in 36% to 67% of critically ill patients depending on the definition used.

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