ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    A prospective study of elevated blood c-reactive protein and d-lactate Biomarkers for intestinal blockage bowel gangrene prediction


    Dr. Sangamesh Kamthane, Dr. Baswesh Patil
    JCDR. 2022: 783-787

    Abstract

    Intestinal blockage is a prevalent clinical issue frequently encountered in the field of surgery. A significant consequence associated with intestinal obstruction is the occurrence of strangulation, which necessitates the surgical procedures of resection and anastomosis of the affected intestine segment. This study aims to investigate the potential utility of a combination of elevated serum c-reactive protein and d-lactate. Materials and Methods: This study was conducted as a prospective single-center study. The present investigation was carried out at Department of General Surgery, Mahavir Institute of Medical Sciences, Telangana, India spanning the period from July 2021 to June 2022. The present investigation encompasses a cohort of 50 individuals who have clinical manifestations consistent with intestinal blockage and strangulation. Results: The prevalence of emesis among the patient population was 52%, with the remaining 48% of patients reporting no instances of vomiting. Approximately 45% of the individuals had symptoms of obstipation, while the remaining instances did not manifest this particular symptom. Abdominal distension was observed in 48% of the cases, whilst the remaining 52% did not exhibit abdominal distension. In 60% of the cases, the presence of guarding was seen, whilst the remaining cases did not exhibit any signs of guarding or rigidity. Conclusion: Strangulation is the most serious disease complication that may necessitate emergency surgery. In acute intestinal strangulation, time is crucial. Early diagnosis and treatment improve prognosis. Clinical evaluation and team expertise determine strangulation diagnosis. Bowel Gangrene in Intestinal Obstruction can be predicted by serum LDH and CRP.

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    Volume & Issue

    Volume 13 Issue 6

    Keywords