Abstract

Gallbladder is one of the organs having a wide spectrum of diseases ranging from calculi and its complications, non-inflammatory, inflammatory to the neoplastic lesions. AIMS AND OBJECTIVES: The aim is to study histopathological spectrum of various gall bladder lesions. MATERIALS AND METHODS: It was a prospective study carried out from March 2023 to August 2023. A series of 149 cholecystectomies specimen were examined grossly and histopathologically. RESULTS: In our study, out of the 149 cases the most common histopathological lesion of gall bladder was chronic cholecystitis with cholelithiasis i.e. 113 cases (75.8%). Chronic cholecystitis without cholelithiasis was seen in 18 cases (12.0%), acute on chronic cholecystitis was seen in 14 cases i.e. 9.3%, adenocarcinoma of gall bladder was seen in 02 cases i.e. 1.3% and adenosquamous carcinoma was seen in 0.6%. CONCLUSION: Gallbladder histopathology includes a variety of lesions. These findings were more common in females and present mostly in the 3rd to 5th decade of life. Most common histopathological finding was chronic cholecystitis and most of the lesions of gallbladder were associated with gallstones. It must be noted that prompt detailed histopathological analysis of the cholecystectomy specimens will help to confirm the benign nature of the disease or to detect any precursors of malignancy

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