ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    A prospective study on vertical transmission of sars-cov-2 in pregnancy in a tertiary referral centre in south india


    Pio James , Reeti Rajan, Sarada Devi KL , Nandini VR , Sreekumari R
    JCDR. 2023: 1048-1053

    Abstract

    t Purpose: The purpose of this study was to determine the possibility of vertical transmission of COVID-19 from COVID-19 positive mothers to new-borns and the associated factors. Methods: This prospective observational study included a total of 128 antenatal COVID-19-positive women. The present study was conducted in a tertiary-care public hospital in south India. This study evaluated the SARS-CoV2 positivity rate in neonates born to SARS-CoV-2-positive mothers who tested RT-PCR positive for this virus in their nasopharyngeal swab. During their hospital stay, these neonates' clinical outcomes were also evaluated. Result: Out of 128 pregnancies, 45 study subjects' placenta specimens were COVID-19 positive, 3 neonates and 2 stillborn were RTPCR positive, and 1 neonate's cord blood was also positive. As among 4 stillbirth babies, 2 stillbirth babies were COVID-19 positive therefore there is a statistically significant relationship between stillbirth and vertical transmission (p = 0.007). In the present study, all COVID-19-positive babies were preterm, therefore there is statistically significance between preterm and vertical transmission (p = 0.00). Conclusion: This study demonstrated that there is a possibility of vertical transmission of COVID-19 from COVID-19 positive mothers to new-borns

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    Volume 14 Issue 5

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