Abstract

In order to maintain arterial pressure during hysterectomies under sub-arachnoid block, we aimed to evaluate and compare the efficacy of prophylactic infusions of ephedrine and phenylephrine. Methods: The current study involved 80 patients who were having spinal anaesthesia for elective hysterectomies and who had physical statuses of Grade I and Grade II according to the American Society of Anaesthesiologists. Phenylephrine 15 micrograms/min, Group P. Group E: 1.5 mg/min of ephedrine. Blood pressure measurements were taken in both groups, and the results are shown as mean standard deviation. Results: Phenylephrine and ephedrine prophylactic infusions were successful in keeping arterial pressure within 20% of the baseline. Ephedrine group required a larger additional bolus dosage than phenylephrine group. Phenylephrine caused a decrease in heart rate, whereas ephedrine caused an increase. Conclusion: Although both medications were successful in keeping arterial blood pressure within a normal range, phenylephrine is more effective than ephedrine and requires less of an extra bolus dosage

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