Journal of Cardiovascular Disease Research
A RANDOMISED CONTROLLED TRIAL OF ONDANSETRON AND LIDOCAINE FOR PROPOFOL INJECTION PAIN
Brijesh Tiwari, Akshata PJ, Pranchil Pandey
JCDR. 2023: 1314-1319
Abstract
The induction of general anesthesia often results in discomfort due to the infusion of propofol. It has been reported that between 28% and 90% of people experience discomfort upon receiving an injection [1]. The best results were achieved by first administering lidocaine and then occluding the veins prior to injecting propofol. Pain relief from propofol injection was significantly affected by ondansetron. We postulated that giving ondansetron before injecting propofol would make the latter more bearable.
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