ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    A Randomized Controlled Trial Comparing the Prevention of Febrile Seizures in Children with Intermittent Oral Levetiracetam Versus Clobazam


    Singireddy Abhigna Reddy, Satya Gayatri Yarlagadda, T. Ananth
    JCDR. 2023: 3221-3227

    Abstract

    When a kid between the ages of 6 months and 5 years old experiences a generalized seizure that lasts less than 15 minutes and does not recur within 24 hours but is not preceded by or related to an acute sickness of the neurological system, this is known as a simple febrile seizure. Febrile seizures are the most common type of epilepsy in youngsters. Material and Methods: Children having a previous episode of febrile seizures who are seen in an outpatient paediatric clinic. This randomised controlled experiment did not hide its identity from participants. The research was carried out in Department of Pediatrics, Bhaskar Medical College & General Hospital, Moinabad, Yenkapally, Telangana, India. Research was conducted from November 2021 to October 2022. Simplified random sampling was used to choose the study participants. The randomization process will be carried out by a computer. Results: Subjects were children aged 6 months to 5 years old who had a history of febrile seizures, defined as two or more episodes of febrile seizures in the previous 6 months, with at least one seizure recurrence in the previous 2 weeks. The primary purpose of this study is to compare the effectiveness of oral levetiracetam and clobazam in the treatment of febrile seizures in children, as well as to determine the frequency with which such seizures return after a follow-up period of 48 weeks. Conclusion: While both medicines were effective in reducing the frequency of repeat febrile seizures, the study found that clobazam was significantly less effective than levetiracetam.

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    Volume & Issue

    Volume 14 Issue 1

    Keywords