Abstract

Background: Sarcomas are rare and heterogeneous group of malignant tumour of mesenchymal origin comprises of less than 1% of all adult and 15% of paediatric malignancies. There are more than 80 histological types and subtypes of which approximately 75% of new cases arise from soft tissue and rest arise from bone. Materials and Methods: This prospective study was conducted in Assam Medical College and Hospital, Dibrugarh from December 2022 to November 2023. A detailed history of cases with prior informed consent was taken and appropriate investigations such as routine blood investigations, USG of limb, MRI, core needle biopsy was done. Patients were followed up with operative intervention, chemotherapy and radiotherapy and post-operative complications, if any. Results: The study that out of 40 cases, 26 (65%) cases were female and the rest 14 (35%) cases were male. Majority of the patients presented with soft tissue sarcoma involving lower extremities (57.5%) followed by upper extremities (30%), trunk (7.5%), retroperitoneum (2%). The most common type of tumour in males was epitheliod type (10%) and in female was desmoid type (22.5%). The majority of patients underwent wide local excision (35%). Conclusion: Treatment of soft tissue sarcoma of extremities requires proper planning. Plan of possible surgery should be done before biopsy with curative intent and limb sparing in mind. Adequate resection margin should be ensured during surgery to prevent recurrences. Adjuvant RT will not rescue inadequate resection. Ultimate goal should be to increase survival, decrease local recurrence, maximize limb function and decrease morbidity.

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