Abstract

Antibiotic resistance is a worldwide public-health emergency. Each year, multidrug resistant pathogens kill about 58,000 infants in India alone. Antibiotic misuse, a global occurrence, is a key generator of drug resistance. Antibiotic resistance is reaching alarmingly high levels across the globe. New resistance mechanisms are evolving and spreading throughout the world, posing a danger to our ability to treat common infectious diseases. Antimicrobial resistance (AMR) has emerged as one of the most important public-health risks, posing serious challenges to the successful prevention and treatment of chronic diseases. antibiotic resistance is mostly induced by antibiotic overuse and misuse. Antimicrobial resistance can develop naturally as a result of ongoing antimicrobial exposure. Natural selection refers to organisms that can adapt to their surroundings, survive, and continue to reproduce. Antimicrobial use and abuse in human, animal, and environmental sectors, as well as the transfer of resistant bacteria and resistance determinants within and between these sectors and around the world, are all causes of antimicrobial resistance. Most antibiotic classes used to treat bacterial infections in humans are also utilized to treat bacterial infections in animals. Given the importance and interdependence of antimicrobial resistance's human, animal, and environmental elements, it is logical to tackle the problem from a One Health perspective. This involves taking steps to ensure that existing antimicrobials continue to be effective by minimizing inappropriate use and controlling the spread of illness

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