Abstract

The plant species Plumbago zeylanica, also known as "Lead wort-white," is a multifunctional herb with a chromosomal number of 24. It is found in the subtropics and tropics and is used as a starter, diuretic, expectorant, and for treating various conditions such as piles, diarrhoea, dysentery, and peptic ulcers also prevent fertility. The leaves of this plant are consumed by locals in Malaya to induce abortion. Oestrogenic chemicals are present in the human diet, leading to discussions on how they can modulate a range of dysfunctions and illnesses influenced by hormones. Since the beginning of written history, people have been looking for an oral contraceptive that would limit human fertility. Despite the wide range of synthetic contraceptives agents available, they cannot be continuously employed due to their adverse effects. In folklore Indian medicine, numerous native medications have been mentioned for the treatment of various reproduction-related conditions. Plumbagin contained in the roots of this plant is responsible for antifertility and uterine action, according to a literature review. In this study, the stems of P. rosea were assessed for potential antifertility effects. If the medication was found to be effective, the removal of this avoiding the use of an abortioninducing plant would be beneficial. In Europe today, the pill is one of the most frequently used methods of birth control, with 19.1% of women between the ages of 15 and 49 taking it on average. Since the introduction of three new generations of oral contraceptives that work together (COCs) in 1960, it has become necessary to use only selected, physiologically active botanical compounds that act as fertility-regulating agents safe and not disrupt the regular cycles of reproduction.

Description