Abstract

Acute respiratory failure (ARF) is a common cause of admission to intensive care unit (ICU) that occurs due to several reasons. Among ICU patients, 40-65% patients need mechanical ventilation during their ICU stay. Mechanical ventilation (MV) is cornerstone for management of acute respiratory failure. Aims and objectives: To determine the clinical profile and predictors of outcome in cardiac patients with preserved ejection fraction requiring mechanical ventilation in a tertiary medical care unit of central India. Design - Observational longitudinal study. Methods: This was a longitudinal study conducted in Department of Medicine, Gandhi Medical College, Bhopal. A total of 100 patients in medical ICU requiring mechanical ventilation were included in the study. Data was entered and analyzed. Results: 20.83 patients per 100 patients required mechanical support among those admitted in ICU. Mean age was 46.88 ±19.58 years with male (57%) predominance. Association between patient outcome with sepsis (p<0.001), Ventilator associated pneumonia (p<0.001), presence of pneumothorax (p<0.001), extubatuion trial (p<0.001) and presence of comorbidities (p<0.001) was found to be statistically significant. Conclusion: This study may contribute to better knowledge of risk factors, better ICU environment, proper use of ventilators and the measures to prevent of complications arising during ventilation that can have a bearing on the patient’s outcome.

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