Abstract

Pain upon injection with propofol is a typical problem that can be quite painful to the patient. However, propofol is a popular intravenous anaesthetic induction drug that offers a smooth, quick induction with rapid clearance and recovery. Inducing agents like ketamine, which is a derivative of the drug phencyclidine, and dexmedetomidine hydrochloride, which is an imidazole molecule, are both examples of the drug class known as alpha 2 agonists. In the current study, a comparison was made between the efficacy of ketamine (0.5 mg/kg) and dexmedetomidine (0.5 mcg/kg) in lowering the severity of pain caused by propofol injection and preventing its occurrence. Ketamine was given at a dose of 0.5 mg/kg, while dexmedetomidine was given at 0.5 mcg/kg.

Description