Abstract

The cardiovascular complications of sickle cell disease (SCD) are being recognized more often and include cardiac enlargement, myocardial ischemia, biventricular dysfunction, and pulmonary hypertension among others. Cardiovascular manifestations of SCD have been attributed to chronic hemolytic anemia, which is typically found in this disorder. Aim & Objective: 1. To evaluate ECG and 2D Echo abnormalities in patients with sickle cell Disease.2. To study of Clinical profile of sickle cell disease. Method: Study design: Observational study. Study setting: Department of General Medicine, Shri Vasantrao Naik Govt. Medical College, Yavatmal. Study duration: 2 years from December 2020 to December 2022. Study population: The study population included all the cases with sickle cell disease patients visiting OPD and admitted at a tertiary care center such cases included in the study. Sample size: 100. Results: majority of cases were found in 12-30 years age group e.g. 42 cases (42%) followed by 24 cases in 31-45 years age group,19 cases in 46-60 years age group and 15 cases in >60 years age group. Most of cases were males e.g. 64 cases (64%) and 36 cases were females (36%). majority of cases presented with T-inversion 34 cases followed by sinus tachycardia 24 cases, Left axis deviation 22 cases, right axis deviation 14 cases,12 right ventricular hypertrophy,10 cases with left ventricular hypertrophy, 9 cases with arrhythmia,5 sinus bradycardia,5 cases with P-pulmonale, low voltage complex 3 cases,Poor progression of R-wave 2 cases and P-mitrale 1 case. majority of cases presented with pulmonary hypertension 34 cases followed by 22 cases presented with right ventricular dilatation,20 cases with left ventricular dilatation left atrial dilatation 16 cases, Left ventricular hypertrophy 14 cases, Regional motion wall abnormality 2 cases. majority of cases complained joint pain 60 cases followed by chest pain 42 cases, palpitation 38 cases, breathlessness 38 cases and fever 22 cases Conclusions: Majority of cases were found in 12-30 years age group. Most of cases were males. Majority of cases presented with T-inversion. Most common Cardiographic changes were pulmonary hypertension

Description