Abstract

Urinary bladder lesions may be either cancerous or non-neoplastic. Urothelial carcinoma is the most frequent form, accounting for 90% of bladder primary tumors. Other types of epithelial bladder cancers include squamous cell carcinomas, mixed urothelial carcinoma with squamous differentiation, adenocarcinomas, and small cell carcinomas. Our work aims to define the histomorphological spectrum of urinary bladder lesions in TURBT and cystoscopic biopsy specimens, as well as to investigate the relationship between smoking habits and urinary bladder malignancies. Methodology: This is a retrospective and prospective observational research of the histomorphological spectrum of urinary bladder lesions conducted in the Department of Urology and department of pathology of a tertiary care teaching hospital over a three-year period. A total of 83 biopsies were performed. The patient provided a comprehensive clinical history, with a focus on his smoking history. Patients of all ages with urinary bladder lesions who attended a urology department and had undergone or were undergoing TURBT/cystoscopic biopsy were included in the research, whereas autolyzed and insufficient specimens were excluded.

Description