Journal of Cardiovascular Disease Research
A Study of Histopathological Changes in Diabetic and Nondiabetic Cadaveric Pancreas with Respect to Diabetic Status
Dr. Baneswar Baro, Dr.Rupam Pegu,Dr. Bornali Hazarika,Dr. Usha Sarma,Dr. Gunamani Rabha, Simanta Kalita
JCDR. 2024: 3826 -3835
Abstract
Background An islet of Langerhans is a mass of polyhedral cells, located in the vicinity of fenestrated capillaries and a rich autonomic innervation. Though the numbers of islets in human pancreas is about or more than 1-2 millions, its distribution within the different parts of pancreas varies with maximum numbers present within the tail area. The beta cells are the most common and account for 50-80% of the cells in the islets. Beta cells mainly secrete insulin and alpha cells secret glucagon.
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