Abstract

The coronavirus strain SARS-COV2, also known as COVID-19, is responsible for the recent coronavirus sickness with various pathological conditions like coagulation abnormalities, mainly thrombotic complications, inflammation, and long-term pulmonary outcomes. Material methods: An observational, cross-sectional study was conducted in Department of Respiratory Medicine, National Institute of Medical Science and Research, Jaipur among COVID-19 patients. Patients of age 21-60 years who have suffered with COVID-19 diseases in past 18 months have been evaluated. All statistical analysis was performed in SPSS (statistical package for social sciences) version23. Results: From the results, elevated D-dimer and Factor VIII levels above normal ranges were noted in 27% and 48% of patients respectively, the results also showed that COVID-19 vaccination preceding SARS-CoV-2 infection show statistically significant differences in the outcome of the disease. Conclusion: The study findings among COVID-19 patients showed that hypercoagulability, endotheliopathy, and inflammation extend well beyond acute SARS-CoV-2 infection, where recovered COVID-19 patients may develop long-term thrombotic and cardiovascular complications. Hence the need for robust public health measures and sound primary prevention policies in preventing SARS-CoV-2 infection as well as appropriate follow-up strategies for recovered patients.

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